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CLINICAL

Clinical and functional studies of the medical, psychosocial, and economic effects of spinal cord injury or disease, and / or interventions proposed to alleviate these effects
 
A Metabolomics Approach to Diagnose Multiple Sclerosis
Robert Powers PhD
University of Nebraska
Lincoln, NE
$150,000

Multiple sclerosis (MS) treatments are time sensitive and require early intervention to impede the accumulation of disabilities and to improve the long-term prognosis of an MS patient. Unfortunately, a correct diagnosis of MS is commonly delayed (upwards of years) because of MS’s similarity to numerous other diseases and the diversity of symptoms experienced by MS patients. But, by far, the overwhelming reason for routine delays in obtaining a correct diagnosis of MS is the complete lack of a simple, accurate, and efficient diagnostic protocol. Instead, diagnosing MS is challenging and error prone; relying on a complex combination of expensive, invasive, and risky tests and difficult patient observations. To remedy this problem, we propose to identify a unique chemical fingerprint in a patient’s urine sample to provide a reliable and early diagnosis test for MS, and to help guide personalized treatments for MS patients.

 

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