Cortical Plasticity After Spinal Cord Injury
Hang Jin Jo PhD
University of Miami Miller School of Medicine
Several neuromodulatory therapies are currently used in humans with spinal cord injury (SCI) alone or in combination with training to promote hand motor recovery. Although these approaches have resulted in improvements in hand voluntary motor output and other related body functions it is clear that the improvements are limited and there is a need to develop novel interventions. Here, we propose a new approach that target cortical connections to spared descending motor pathways as a mechanism for recovery. We will use a motor task together with noninvasive-paired cortical stimulation to target corticospinal descending volleys during gross grasping behaviors in humans with and without SCI.